Ground vehicles are the main sources of noise and infrasound in residential areas. Numerous published works are devoted to studies of audible sound, its sources in vehicle, and development of measures to its reduction. The authors believe that the problem of infrasound occurrence and propagation in residential areas and, hence, its negative impact on humans and ambient environment is underestimated. Development of predictions and experimental methods of studying infrasound generating mechanism and environmental monitoring of this negative factor are an urgent issue. Significant portion of acoustic emission from a vehicle is comprised for infrasound and low frequency range. Internal and external infrasound of vehicle has been measured. Prediction model has been proposed and the influence of vehicle design features on infrasound level has been estimated. Predictions of external infrasound generating mechanism of vehicles reveal that its frequency and level depend on driving speed, drag coefficient, vehicle body length, Strouhal number. Important sources of vehicle infrasound are wheels which execute rotation and progressive movement in airstream. Five wheel harmonics have been calculated for motor vehicles at various driving speeds, the existing dependences are detected. It has been demonstrated that the regulatory levels of infrasound can be exceeded only in residential areas adjacent to traffic flow with driving speeds higher than 80 km/h. The results of field studies of infrasound level on the streets of Moscow are presented. Recommendations on development of environmental monitoring and main approaches to reduce infrasound in urban environment are given