National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support N.I.H. Extramural Disease Models Animal Apoptosis / drug effects Knockout lymphohistiocytosis etoposide / administration & dosage hemophagocytic / drug therapy* dna-binding proteins / genetics interferon-gamma / biosynthesis t-lymphocytes / immunology* macrophages / drug effects dendritic cells / immunology lymphocyte activation / immunology* apoptosis / immunology pmid:24259502 pmc4177106 doi:10.4049/jimmunol.1302282 theodore s johnson catherine e terrell michael b jordan antigen presentation / drug effects antigen presentation / immunology dendritic cells / drug effects etoposide / pharmacology* lymphocyte activation / drug effects* lymphocytic choriomeningitis virus hemophagocytic / genetics hemophagocytic / immunology* macrophage activation / drug effects macrophage activation / immunology macrophages / immunology t-lymphocytes / drug effects* topoisomerase ii inhibitors / administration & dosage topoisomerase ii inhibitors / pharmacology