Randomised clinical study: oral aspirin 325 mg daily vs placebo alters gut microbial composition and bacterial taxa associated with colorectal cancer risk
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Randomised clinical study: oral aspirin 325 mg daily vs placebo alters gut microbial composition and bacterial taxa associated with colorectal cancer risk

Prizment AE;Staley C;Onyeaghala GC;Vivek S;Thyagarajan B;Straka RJ;Demmer RT;Knights D;Meyer KA;Shaukat A;Sadowsky MJ;Church TR;;
alimentary pharmacology & therapeutics 2020 pp. -
245
ae2020alimentaryrandomised

Abstract

Compared to placebo, aspirin intake influenced several microbial taxa (Ruminococcaceae, Clostridium XlVa, Parabacteroides and Dorea) in a direction consistent with a priori hypothesis based on their association with CRC. This suggests that aspirin may influence CRC development through an effect on t …

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National Center for Biotechnology Information NCBI NLM MEDLINE pubmed abstract nih national institutes of health national library of medicine pmid:32770859 doi:10.1111/apt.16013 anna e prizment christopher staley timothy r church

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